Turmeric
for Hashimoto's
Excess inflammation is always present in Hashimoto’s
Thyroiditis (the suffix "itis" denotes inflammation in the
thyroid gland), and intestinal permeability has been found as a common factor
in every case of autoimmunity. In some cases, people with Hashimoto’s
may also have heavy metal toxicity. Turmeric can be helpful in reducing
whole body inflammation, healing the gut, as well as detoxifying from heavy
metals.
Studies of the effect of curcumin, the active
ingredient of turmeric on the thyroid gland and autoimmunity have
showed encouraging results.
1. Research
shows that curcumin can help to protect the intestinal barrier from
invasion by bacterial infection and can help heal a leaky gut.
2. According
to a 2014 study in the journal Food Chemistry and
Toxicology; "Curcumin reduces
the hepatotoxicity induced by arsenic, cadmium, chromium,
copper, lead and mercury, prevents histological injury,
lipid peroxidation and glutathione (GSH) depletion, maintains the
liver antioxidant enzyme status and protects against mitochondrial
dysfunction."
3. Curcumin showed
tumor inhibiting activity in thyroid cancer.
4. Curcumin was
protective against the genetic damage and side effects induced by
radioactive iodine that is sometimes used to treat Graves’ disease
5. Curcumin has
anti-inflammatory benefits that can be helpful in down-regulating autoimmune
conditions. Specifically, curcumin produces an anti-inflammatory
effect by down-regulating Th-1 cytokines (TNF-A, IL-1, 2, 6, 8, 12),
which may be overactive in Hashimoto’s. Curcumin has been found to
reduce joint inflammation in the Th-1 autoimmune condition rheumatoid
arthritis. Additionally, it seems to have therapeutic anti-inflammatory effects
in a variety of gastrointestinal conditions, showing improvement in Crohn’s disease
(Th-1), Ulcerative colitis (Th-2) and irritable bowel syndrome.
Survey Results
In my survey of 2232 people with Hashimoto's,
680 people reported that they had tried curcumin. 56% reported that it was
helpful, 40% did not see a change in how they felt, while 3% said it made them
feel worse.
When asked about the specific benefits seen from the use
of turmeric, 64% of people reported that it helped them with reducing pain
symptoms. Other positive benefits were an increase in energy (seen in 35%),
improvement in mood (seen in 34%), and an improvement in thyroid antibodies
(12.5%).
Pain is the most obvious manifestation of inflammation in
the body, so I'm not surprised that those that had pain saw an improvement
with curcumin use. While most people with Hashimoto's do
have inflammation, only some will present with pain symptoms. Poor energy, mood
changes and thyroid antibodies are also indicative of inflammation and it was
encouraging that curcumin also impacted those parameters, but it
should be noted that improvements in those symptoms may be less obvious to
notice, and may also take a bit longer to manifest.
While curcumin can also boost glutathione (an
antioxidant that's often depleted in Hashimoto's), reduce inflammation,
help with healing the gut, and detoxifying from heavy metals, it's
difficult to assess these improvements symptomatically.
While most people with Hashimoto's will benefit
from the addition of turmeric, I would say that if you are currently
experiencing pain, you will see the most benefit.
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